Queen Latifah is set to host a new daytime talk show, which Flavor Unit, her company with Shakim Compere, will co-produce with Will Smith.

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Ms. Winfrey's new show, which could air as many as two or three times a week, will take Ms. Winfrey out of the studio setting that has been her home for 25 years and follow her around the globe for conversations in places such as Egypt and China.